 | 
|
| |
|
Titel: Epidemiologin för frakturer [summary] (serie: Tema osteoporos) 2006 nr 40 sid 2956-8
|
Summary:
200 milj. subjects worldwide and 30% of postmenopausal women in the EU-region have osteoporosis and 40-45% are expected to suffer from one or more fragility fracture during their remaining lifetime. The male risk is approximately the half. From 1.5 milj. hip fractures worldwide 1990, the number is estimated to 2.6 milj. 2025 and over 6 milj. 2050. The main part of these will occur in Asia and Latin America due to a rapid ageing population. Approximately one milj. incident hip fractures occur in EU each year. The highest risk is found in Scandinavia, although some recent studies report a stable or decreasing incidence. Sweden has an estimated 70 000 fragility fractures yearly, 18000 of which are hip fractures. Future changes may include an increase of male fractures, mean fracture age and the relative number of trochanteric fractures. The large birth-cohorts from the 1940's will influence the number of fractures after 2010, independent of changes in age-adjusted risk. Unknown cohort effects may modify this pattern.
Owe Löfman
Correspndence:
Owe Löfman, Prof, University of Life Sciences, Dept Math Sciences and Technology, Box 5003, -1432 Ås, Norge, E-mail: owe.lofman@umb.no, Fax. +47 64965401
Referenser:
1. Cooper C. Epidemiology of osteoporosis. Osteoporos Int 1999;9 Suppl 2:S2-8.
2. Melton LJ, 3rd, Chrischilles EA, Cooper C, Lane AW, Riggs BL. Perspective. How many women have osteoporosis? J Bone Miner Res 1992;7(9):1005-10.
3. Johnell O, Kanis JA. An estimate of the worldwide prevalence, mortality and disability associated with hip fracture. Osteoporos Int 2004;15(11):897-902.
4. Gullberg B, Johnell O, Kanis JA. World-wide projections for hip fracture. Osteoporos Int 1997;7(5):407-13.
5. Cooper C, Campion G, Melton LJ, 3rd. Hip fractures in the elderly: a world-wide projection. Osteoporos Int 1992;2(6):285-9.
6. Kanis JA, Johnell O. Requirements for DXA for the management of osteoporosis in Europe. Osteoporos Int 2005;16(3):229-38.
7. Delmas P, D.Fraser,M. . European Union challenges memberstates to fight the silent epidemic of osteoporosis. Eurohealth 1998;4(4):1-4.
8. Kanis JA, Johnell O, De Laet C, Jonsson B, Oden A, Ogelsby AK. International variations in hip fracture probabilities: implications for risk assessment. J Bone Miner Res 2002;17(7):1237-44.
9. Thorngren KG. Fractures in the elderly. Acta Orthop Scand Suppl 1995;266:208-10.
10. Hagenfeldt KA, V. Eksell, S. Johansson,C. Johnell,O. Ljunggren,Ö. Marké,L Å. Möller, M. Mørland,B. Nilsson,K. Ringertz,H.Strender, L E.Sääf, M. Sønbø Kristiansen, I.Zethraeus, N. . Osteoporos - prevention, diagnostik och behandling. Gul rapport: Statens beredning för medicinsk utvärdering, 2003.
11. Lofman O, Berglund K, Larsson L, Toss G. Changes in hip fracture epidemiology: redistribution between ages, genders and fracture types. Osteoporos Int 2002;13(1):18-25.
12. Riggs BL, Melton LJ, 3rd. Involutional osteoporosis. N Engl J Med 1986;314(26):1676-86.
13. Madhok R, Melton LJ, 3rd, Atkinson EJ, O'Fallon WM, Lewallen DG. Urban vs rural increase in hip fracture incidence. Age and sex of 901 cases 1980-89 in Olmsted County, U.S.A. Acta Orthop Scand 1993;64(5):543-8.
14. Schroder HM, Petersen KK, Erlandsen M. Occurrence and incidence of the second hip fracture. Clin Orthop Relat Res 1993(289):166-9.
15. Ismail AA, O'Neill TW, Cooper C, Finn JD, Bhalla AK, Cannata JB, et al. Mortality associated with vertebral deformity in men and women: results from the European Prospective Osteoporosis Study (EPOS). Osteoporos Int 1998;8(3):291-7.
16. Ensrud KE, Thompson DE, Cauley JA, Nevitt MC, Kado DM, Hochberg MC, et al. Prevalent vertebral deformities predict mortality and hospitalization in older women with low bone mass. Fracture Intervention Trial Research Group. J Am Geriatr Soc 2000;48(3):241-9.
17. Hasserius R, Karlsson MK, Nilsson BE, Redlund-Johnell I, Johnell O. Prevalent vertebral deformities predict increased mortality and increased fracture rate in both men and women: a 10-year population-based study of 598 individuals from the Swedish cohort in the European Vertebral Osteoporosis Study. Osteoporos Int 2003;14(1):61-8.
18. Hallberg I, Rosenqvist AM, Kartous L, Lofman O, Wahlstrom O, Toss G. Health-related quality of life after osteoporotic fractures. Osteoporos Int 2004;15(10):834-41.
19. Lofman O, Larsson L, Toss G. Bone mineral density in diagnosis of osteoporosis: reference population, definition of peak bone mass, and measured site determine prevalence. J Clin Densitom 2000;3(2):177-86.
20. Cummings SR, Black DM, Nevitt MC, Browner W, Cauley J, Ensrud K, et al. Bone density at various sites for prediction of hip fractures. The Study of Osteoporotic Fractures Research Group. Lancet 1993;341(8837):72-5.
21. Kanis JA, Borgstrom F, De Laet C, Johansson H, Johnell O, Jonsson B, et al. Assessment of fracture risk. Osteoporos Int 2005;16(6):581-9.
22. Kanis JA, Johnell O, Oden A, Sembo I, Redlund-Johnell I, Dawson A, et al. Long-term risk of osteoporotic fracture in Malmo. Osteoporos Int 2000;11(8):669-74.
23. Zain Elabdien BS, Olerud S, Karlstrom G, Smedby B. Rising incidence of hip fracture in Uppsala, 1965-1980. Acta Orthop Scand 1984;55(3):284-9.
24. Parkkari J, Kannus P, Niemi S, Pasanen M, Jarvinen M, Luthje P, et al. Increasing age-adjusted incidence of hip fractures in Finland: the number and incidence of fractures in 1970-1991 and prediction for the future. Calcif Tissue Int 1994;55(5):342-5.
25. Hedlund R, Ahlbom A, Lindgren U. Hip fracture incidence in Stockholm 1972-1981. Acta Orthop Scand 1986;57(1):30-4.
26. Giversen IM. Time trends of age-adjusted incidence rates of first hip fractures: a register-based study among older people in Viborg County, Denmark, 1987-1997. Osteoporos Int 2006;17(4):552-64.
27. Baudoin C, Fardellone P, Sebert JL. Effect of sex and age on the ratio of cervical to trochanteric hip fracture. A meta-analysis of 16 reports on 36,451 cases. Acta Orthop Scand 1993;64(6):647-53.
28. Michaelsson K, Weiderpass E, Farahmand BY, Baron JA, Persson PG, Ziden L, et al. Differences in risk factor patterns between cervical and trochanteric hip fractures. Swedish Hip Fracture Study Group. Osteoporos Int 1999;10(6):487-94.
29. Fox KM, Magaziner J, Hebel JR, Kenzora JE, Kashner TM. Intertrochanteric versus femoral neck hip fractures: differential characteristics, treatment, and sequelae. J Gerontol A Biol Sci Med Sci 1999;54(12):M635-40.
30. Keene GS, Parker MJ, Pryor GA. Mortality and morbidity after hip fractures. Bmj 1993;307(6914):1248-50.
31. Melton LJ, 3rd. Atkinson, E.J. Madhok, R. Downturn in hip fracture incidence. Public Health Rep 1996;111:146-50.
32. Naessen T, Parker R, Persson I, Zack M, Adami HO. Time trends in incidence rates of first hip fracture in the Uppsala Health Care Region, Sweden, 1965-1983. Am J Epidemiol 1989;130(2):289-99.
33. Nilsson R, Lofman O, Berglund K, Larsson L, Toss G. Increased hip-fracture incidence in the county of Ostergotland, Sweden, 1940-1986, with forecasts up to the year 2000: an epidemiological study. Int J Epidemiol 1991;20(4):1018-24.
34. Huusko TM, Karppi P, Avikainen V, Kautiainen H, Sulkava R. The changing picture of hip fractures: dramatic change in age distribution and no change in age-adjusted incidence within 10 years in Central Finland. Bone 1999;24(3):257-9.
35. Lofthus CM, Osnes EK, Falch JA, Kaastad TS, Kristiansen IS, Nordsletten L, et al. Epidemiology of hip fractures in Oslo, Norway. Bone 2001;29(5):413-8.
36. Nymark T, Lauritsen JM, Ovesen O, Rock ND, Jeune B. Decreasing incidence of hip fracture in the Funen County, Denmark. Acta Orthop 2006;77(1):109-13.
37. Rehnberg L, Olerud C. Incidence of hip fractures in the elderly. Uppsala County 1980-1987. Acta Orthop Scand 1990;61(2):148-51.
 2956 |
 2957 |
 2958 |